Category Biostatistics

Bayesian Methodology in the Genetic Age

At its simplest, statistical inference is used to draw conclusions from the data in our samples and project these findings to populations for which we do not have data. Having previously discussed some of the primary differences between Bayesian and Frequentist (Classical) schools of inference, one can summarise the fundamental differences between the two approaches […]

Bayesian Vs. Frequentist statistics and the case that never was…

There’s a lot of truth in the quote above, well the bit about statistics at least – I don’t think anyone else, anywhere at any time has ever considered computer engineering a sexy occupation. With that said, sexy or not, statistical analysis has become an essential tool to researchers of all scientific disciplines so it […]

Cholesky decomposition of variance-covariance matrices in the classic twin study

Cholesky Decomposition… Twin and adoption studies rely heavily on the Cholesky Method and not being au fait in the nuances of advanced statistics, I decided to have a fumble around the usual online resources to pad out the meagre understanding I had gleaned from a recent seminar. Que the overly familiar and equally frustrating routine of combing […]