Monthly Archives: July 2012

Bayesian Methodology in the Genetic Age

At its simplest, statistical inference is used to draw conclusions from the data in our samples and project these findings to populations for which we do not have data. Having previously discussed some of the primary differences between Bayesian and Frequentist (Classical) schools of inference, one can summarise the fundamental differences between the two approaches […]

Bayesian Vs. Frequentist statistics and the case that never was…

There’s a lot of truth in the quote above, well the bit about statistics at least – I don’t think anyone else, anywhere at any time has ever considered computer engineering a sexy occupation. With that said, sexy or not, statistical analysis has become an essential tool to researchers of all scientific disciplines so it […]

White/Grey Matter as a Neuronal Phenotype

Affordable whole genome sequencing is nearing ever closer and with it an urgency to develop more robust and quantitative diagnostic tools that might aid in objectively classifying neurological disorders. Biochemical & structural phenotypes that can be  readily and cheaply tested for is a worthy, though frustratingly elusive, pursuit across a wide spectrum of disorders. One such […]